What socioeconomic benefits can be attributed to nursing and midwifery with respect to: mental health nursing, long-term conditions, and role substitution? In order to address this question, the EPPI-Centre carried out a Systematic Rapid Evidence Assessment (SREA) involving a focused review of systematic reviews with a limited search. This systematic review was published by EPPI-Centre in 2010 . Systematic reviews aim to find as much as possible of the research relevant to the particular research questions, and use explicit methods to identify what can reliably be said on the basis of these studies.